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Toxicity of aliphatic amines: structure-activity relationship
H Greim1, D Bury, H J Klimisch
1GSF-Institut für Toxikologie, Oberschleissheim, Germany.
Chemosphere
|May 7, 1998
Abstract:
SARs may enable the evaluation of the toxic potential of chemicals by drawing conclusions from available data on structurally-related chemicals, thus reducing the need for further testing. The Advisory Committee on Existing Chemicals of Environmental Relevance (BUA) [1,2] of the German Chemical Society (Gesellschaft Deutscher Chemiker [GDCh]) has compiled data on the toxicity and ecological impact for several groups of chemicals [3, 4]. In the present review, some common toxicological properties for aliphatic amines were revealed after evaluation and comparison of the toxicity data.