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Related Experiment Videos

Does spinal anesthesia affect cerebral oxygenation during transurethral prostatectomy?

M M Atallah1, A Hoeft, M A El-Ghorouri

  • 1Department of Anesthesia, Faculty of Medicine, University of Mansoura, Egypt.

Regional Anesthesia and Pain Medicine
|May 7, 1998
PubMed
Summary

Transurethral resection of the prostate (TURP) can cause transurethral resection of prostate syndrome (TURS). This study found that reduced cerebral oxygenation during spinal anesthesia may contribute to TURS symptoms, not just fluid absorption.

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Area of Science:

  • Anesthesiology
  • Neurosurgery
  • Urology

Background:

  • Transurethral resection of the prostate (TURP) is a common procedure.
  • Transurethral resection of prostate syndrome (TURS) is a known complication attributed to irrigating fluid absorption.

Purpose of the Study:

  • To investigate the impact of spinal anesthesia and TURP on cerebral oxygen balance.
  • To explore the relationship between cerebral oxygenation and TURS symptoms.

Main Methods:

  • Thirty patients undergoing TURP were enrolled.
  • Jugular bulb oxygen saturation (SjbO2) was monitored using retrograde cannulation.
  • Hemodynamic and blood gas measurements were taken before, during, and after spinal anesthesia.

Main Results:

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  • Spinal anesthesia led to a significant decrease in cerebral perfusion pressure and SjbO2.
  • Eight patients exhibited symptoms consistent with early TURS, showing significantly reduced SjbO2.
  • Reduced SjbO2 levels were observed in 63% and 42% of data points in symptomatic patients.

Conclusions:

  • Neurologic symptoms during TURP under spinal anesthesia may stem from impaired cerebral oxygenation.
  • Cerebral oxygen balance is a critical factor to consider during TURP procedures.
  • Further investigation into the mechanisms of TURS is warranted.