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Cryptococcosis: an unusual opportunistic infection complicating B cell lymphoproliferative disorders
M Melzer1, M Colbridge, F Keenan
1Department of Infection and Tropical Medicine, University of Newcastle Medical School, Newcastle General Hospital, Newcastle upon Tyne, UK.
The Journal of Infection
|November 20, 1998
Abstract:
We report two cases of cryptococcosis in patients with Waldenstrom's macroglobulinaemia and chronic lymphocytic leukaemia that responded to prolonged therapy with systemic amphotericin and flucytosine. Cryptococcosis, although more common in those with impaired cell mediated immunity, should also be considered as a complication in patients with impaired antibody responses.