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Endometriosis with massive ascites

O Muneyyirci-Delale1, G Neil, E Serur

  • 1Department of Obstetrics and Gynecology, Radiology, State University of New York Health Science Center at Brooklyn, 11203, USA.

Gynecologic Oncology
|May 8, 1998
PubMed
Summary
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Endometriosis can cause massive ascites, mimicking cancer. Symptoms like painful periods and pelvic masses are key indicators, but hormonal treatments are often ineffective, necessitating surgical intervention.

Area of Science:

  • Gynecology
  • Reproductive Medicine
  • Surgical Oncology

Background:

  • Endometriosis is a chronic inflammatory condition.
  • Massive ascites is a rare complication of endometriosis.
  • Ascites in women with pelvic masses often raises suspicion for malignancy.

Observation:

  • This study presents 4 cases of endometriosis with massive ascites and reviews 27 literature cases.
  • Patients often presented with symptoms suggestive of neoplastic disease.
  • Classical endometriosis symptoms such as dysmenorrhea and cul-de-sac nodularity were also present.
  • Ascites and other symptoms exacerbated during menses.

Findings:

  • Endometriosis-associated ascites can mimic ovarian cancer.
  • Hormonal therapy, including gonadotropin-releasing hormone (GnRH) agonists, showed unsatisfactory response rates.

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  • Recurrent disease and severe complications, including pleural and pulmonary involvement, were common.

    • Implications:

    • Accurate diagnosis of endometriosis-associated ascites is crucial to avoid misdiagnosis of cancer.
    • Management may require a multidisciplinary approach.
    • Further research into effective treatments for this rare complication is warranted.