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Evaluation of endothelial function in postkeratoplasty eyes
J S Saini1, S Mittal, A K Jain
1Department of Ophthalmology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Background And Objective:
To evaluate corneal endothelium function in postkeratoplasty eyes.
Patients And Methods:
Endothelial function was assessed in 23 clear corneal grafts. After a measurable corneal edema was induced by soft contact lens wear, serial pachometric readings were taken for 3 hours to arrive at the percentage recovery per hour (PRPH) index.
Results:
The assessed PRPH values of the clear corneal grafts ranged from 24.6% to 73.0%, with a mean value of 51.8% +/- 12.2%. Of the six corneal grafts that demonstrated an initial PRPH value of less than 47.5%, four became edematous within 6 months of follow-up.
Conclusions:
Assessed PRPH, as an in vivo-measured index of endothelial function, is a valuable method for monitoring endothelial function in postkeratoplasty eyes. The low PRPH index identifies eyes at risk of spontaneous nonimmunologic failures.