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Effect of acidic fibroblast growth factor (aFGF) on phagocytosis in mouse peritoneal macrophages
M Ichinose1, M Sawada, K Sasaki
1Department of Physiology, Shimane Medical University, Japan. michinos@shimane-med.ac.jp
Microbiology and Immunology
|May 8, 1998
Abstract:
The effects of acidic fibroblast growth factor (aFGF) on phagocytosis in peritoneal macrophages from thioglycollate-elicited mice were examined using flow cytometry. aFGF enhanced phagocytosis of fluorescein isothiocyanate-labeled latex particles in a dose-dependent manner. Basic fibroblast growth factor (bFGF) also enhanced phagocytosis. This study suggests that aFGF can modulate an important activity of macrophages.