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Bullous pemphigoid in infancy: case report and literature review
Pediatric Dermatology
|May 8, 1998
Insights
A 2-month-old infant developed bullous pemphigoid on her hands and feet after routine immunizations. This rare infantile condition requires consideration in diagnosing blisters in infants.
Area of Science:
- Pediatrics
- Dermatology
- Immunology
Background:
- Bullous pemphigoid (BP) is a rare autoimmune blistering disease.
- Infantile bullous pemphigoid (IBP) presents differently than adult BP.
- The etiology of IBP is often unclear, but recent-onset cases suggest potential triggers.
Observation:
- A 2-month-old female infant presented with blisters on her hands and feet.
- The onset of symptoms occurred shortly after receiving routine immunizations.
- The clinical presentation was consistent with infantile bullous pemphigoid.
Findings:
- Infantile bullous pemphigoid can manifest on the hands and feet.
- The condition's presentation in infants differs from that in older individuals.
- Prompt diagnosis is crucial for effective management.
Implications:
- Infantile bullous pemphigoid should be considered in the differential diagnosis of neonatal and infant blistering disorders.
- Early recognition and treatment can lead to favorable outcomes.
- Further research into potential triggers, such as immunizations, is warranted.
Abstract:
We report a 2-month-old girl who developed bullous pemphigoid on her hands and feet shortly after receiving her routine immunizations. Infantile bullous pemphigoid has a clinical presentation distinct from bullous pemphigoid seen in older children and should be included in the differential diagnosis of blisters involving the hands and feet. Our patient responded well to topical corticosteroid therapy.