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Progressive sensorineural hearing impairment in systemic vasculitides
S Berrettini1, C Ferri, F Ravecca
1Neuroscience Department, University of Pisa, Italy.
Seminars in Arthritis and Rheumatism
|May 8, 1998
Summary
Progressive sensorineural hearing loss (PSNHL) is a rare complication of systemic vasculitis, affecting 14 patients in this study. Early assessment and treatment, including corticosteroids and immunosuppressants, can improve outcomes.
Area of Science:
- Otolaryngology
- Rheumatology
- Neurology
Background:
- Systemic vasculitis can affect multiple organs, including the auditory system.
- Progressive sensorineural hearing loss (PSNHL) is a potential, though uncommon, manifestation.
Observation:
- 14 out of 673 patients with systemic vasculitis presented with PSNHL.
- Hearing loss was typically bilateral, asymmetrical, sensorineural, and cochlear.
- Vestibular symptoms like unsteadiness and canal paresis/palsy were common.
Findings:
- Systemic corticosteroids and cyclophosphamide showed efficacy in treating PSNHL.
- Methotrexate and plasma exchange were effective for unresponsive cases.
Implications:
- PSNHL can be an early symptom of systemic vasculitis.
- Prompt diagnosis and treatment are crucial for managing hearing loss and improving prognosis in vasculitis patients.