Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intraoperative autotransfusion: equipment, protocols, and guidelines

J Raines, J Buth, D C Brewster

    The Journal of Trauma
    |August 1, 1976
    PubMed
    Summary

    Intraoperative autotransfusion (IAT) offers a safe and effective method for blood volume support. While it can reduce red cell mass and elevate plasma free hemoglobin, these effects are manageable and resolve quickly.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNGM).

    Annals of oncology : official journal of the European Society for Medical Oncology·2022
    Same author

    Zinc Gluconate Induces Potentially Cancer Chemopreventive Activity in Barrett's Esophagus: A Phase 1 Pilot Study.

    Digestive diseases and sciences·2020
    Same author

    Carotid interventions (CEA and CAS) in acute stroke patients: which procedure on which patient.

    The Journal of cardiovascular surgery·2015
    Same author

    Reprinted article "Realistic expectations for patients with stent-graft treatment of abdominal aortic aneurysms. Results of a European multicentre registry".

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2011
    Same author

    Validation of the chronic venous insufficiency quality of life questionnaire in Dutch patients treated for varicose veins.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2011
    Same author

    Factors maintaining heat balance of the clothed man at different grades of activity in the cold.

    Federation proceedings·2010

    Area of Science:

    • Transfusion Medicine
    • Surgical Hemostasis
    • Patient Blood Management

    Background:

    • Intraoperative autotransfusion (IAT) utilizes a patient's own blood collected during surgery for reinfusion.
    • Modified commercial equipment can provide safe and effective IAT.
    • IAT offers several advantages including availability, sterility, compatibility, normothermia, and cost-effectiveness.

    Observation:

    • Red cell mass reduction due to blood loss and hemolysis can occur but is manageable with homologous transfusions.
    • Plasma free hemoglobin is transiently elevated post-IAT but clears within 24 hours.
    • Platelet function may be affected with large volume reinfusions (>3,500 ml), necessitating platelet concentrate supplementation.

    Findings:

    • IAT demonstrates normal red cell survival and no clinical evidence of intravascular coagulopathy.

    Related Experiment Videos

  • Dilutional coagulopathy can occur with massive IAT (>5,000 ml) but is controllable with fresh frozen plasma and platelets.
  • No renal failure, fat emboli, or significant alterations in blood gases were observed; air emboli are a risk mitigated by proper technique and equipment modification.

    • Implications:

    • IAT is not typically necessary for blood loss <1,000 ml.
    • For expected blood loss >3,500 ml, additional blood products (homologous transfusions, platelets, fresh frozen plasma) may be required.
    • As banked blood supplies diminish, IAT may become a standard component of general surgical procedures.