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[Lipid peroxidation processes in chronic bronchitis]
Terapevticheskii Arkhiv
|May 12, 1998
Abstract
Aim:
Comparison of the levels of lipid peroxidation (LPO) products in condensate of the exhaled air (CEA) and in the biopsy samples from the inflammation focus.
Materials And Methods:
Extraction spectrophotometry was used to measure LPO products in CEA and biopsies from 30 males aged 30-60 years suffering from chronic bronchitis and 30 healthy controls of the same age.
Results:
There was activation of local accumulation of isopropanol-soluble LPO products in the bronchopulmonary system accompanied by lowered content of lipoperoxides and high antioxidant activity in CEA.
Conclusion:
Chronic bronchitis is characterized by multidirectional shifts in LPO in the inflammation focus and CEA.