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[Risk factors and the molecular cellular mechanisms of a protracted course in pneumonia]
Terapevticheskii Arkhiv
|May 12, 1998
Abstract
Aim:
Investigation of risk factors and molecular-cellular. mechanisms of development of lingering pneumonia (LP).
Materials And Methods:
Examination covered 202 patients with acute pneumonia and 199 patients with LP.
Results:
LP was characterized by deeper suppression of immunity, restructuring of the lipid bilayer, changed microviscosity and enzymic activity of red cell membranes as a result of infectious-toxic factor, activation of lipid peroxidation, suppression of the antioxidant defense.
Conclusion:
The findings contribute to design of more detailed principles of pathogenetic therapy and prevention of LP.