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Related Experiment Videos

Apparent arterial compliance

C M Quick1, D S Berger, A Noordergraaf

  • 1Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08855-0909, USA.

The American Journal of Physiology
|May 12, 1998
PubMed
Summary
This summary is machine-generated.

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Estimating total arterial compliance is crucial. This study introduces "apparent compliance," a frequency-dependent measure accounting for finite pulse wave velocity, offering a new perspective beyond traditional models.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Hemodynamics

Background:

  • Estimating total arterial compliance is essential for understanding cardiovascular health.
  • Direct measurement of arterial compliance is not feasible.
  • Traditional lumped models (e.g., Windkessel) rely on assumptions of linearity and infinite pulse wave velocity.

Purpose of the Study:

  • To generalize the Windkessel model by incorporating finite pulse wave velocity.
  • To introduce a new concept of "apparent compliance" that describes the pressure-volume relationship as a function of frequency.
  • To analyze the influence of heart rate, peripheral resistance, and pulse wave reflection on this relationship.

Main Methods:

  • Applied transmission theory to a linear arterial system model with finite pulse wave velocity.

Related Experiment Videos

  • Described arterial compliance as a complex, frequency-dependent function relating input pressure to stored volume.
  • Derived the concept of "apparent compliance" from this pressure-volume relationship.

    • Main Results:

    • The generalized Windkessel model incorporates finite pulse wave velocity.
    • Arterial compliance is described as a complex function of frequency.
    • This frequency-dependent relationship is influenced by heart rate, peripheral resistance, and pulse wave reflection.

    Conclusions:

    • Introduced the concept of "apparent compliance" as a frequency-dependent measure.
    • "Apparent compliance" differs from total arterial compliance due to finite pulse wave velocity.
    • This new concept provides a more comprehensive understanding of arterial hemodynamics and complements "apparent pulse wave velocity."