[Properties of gas (CO2) microbubbles made by hand agitation and it's contrast enhancing effect]

The property of gas (CO2) microbubbles made by hand agitation and it's contrast enhancing effect of abdominal organs on gray scale ultrasound are here described. The size of microbubbles of CO2 gas adequately prepared with 5% human serum albumin was nearly 23 microns in mean diameter. However, the size and the density of gas microbubbles are affected with many factors, including mixing times, volume ratio of gas and liquid and the species of gas and liquid. On the other hand, contrast enhancing effect is determined by the size and the density of gas microbubbles. For the adequate evaluation of contrast enhancing effect of abdominal tumors by enhanced ultrasonography, the property of gas microbubbles described as above should be carefully considered.