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[Harmonic imaging]

Y Mine1

  • 1Toshiba Corporation, Medical Engineering Laboratory.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|May 13, 1998
PubMed
Summary
This summary is machine-generated.

Second harmonic imaging uses microbubbles to enhance ultrasound signals, improving visualization of tissue perfusion. This advanced technique offers better contrast for diagnostic ultrasound systems.

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Area of Science:

  • Medical Imaging
  • Biomedical Engineering
  • Acoustics

Background:

  • Microbubbles oscillate nonlinearly in diagnostic ultrasound fields.
  • Ultrasound signals from microbubbles contain strong harmonics at twice the transmitted frequency.
  • Second harmonic imaging enhances tissue-agent contrast.

Purpose of the Study:

  • To evaluate the usefulness of second harmonic imaging in vivo.
  • To assess the potential of second harmonic imaging for visualizing tissue perfusion.

Main Methods:

  • In vivo experiments were conducted.
  • Second harmonic imaging was applied to canine hepatic parenchyma.

Main Results:

  • The hepatic parenchyma was clearly enhanced using second harmonic imaging.
  • Nonlinear motion of microbubbles was observed.

    • Conclusions:

    • Second harmonic imaging significantly improves tissue-agent contrast.
    • This technique can expand diagnostic ultrasound capabilities for tissue perfusion visualization.