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Updated: Aug 17, 2026

Transduction of Human Cells with Polymer-complexed Ecotropic Lentivirus for Enhanced Biosafety
Published on: July 24, 2011
[Molecular biology and transfusional viral safety]
1Institut national de la transfusion sanguine, Paris, France.
Abstract:
In this review we present four fields to which viral molecular biology has contributed: the discovery of blood-borne viruses and the knowledge of the natural history of infection by these viruses; the validation of the results of virological assays used in the biological screening of blood donations; the contribution of molecular biology in inquiries into viral transfusional contamination; the interest of molecular biology in viral transfusional epidemiology. We subsequently deal with the parameters of the discussion on the impact and the feasibility of a systematic screening of several viral genomes in blood donations.
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