Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise-induced changes in protein metabolism

K D Tipton1, R R Wolfe

  • 1Department of Surgery, The University of Texas Medical Branch, Galveston, USA.

Acta Physiologica Scandinavica
|May 13, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Resistance training increases skeletal muscle oxidative capacity and net intramuscular triglyceride breakdown in type I and II fibres of sedentary males.

Experimental physiology·2014
Same author

Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5.

The Journal of physiology·2012
Same author

Preferential utilization of perilipin 2-associated intramuscular triglycerides during 1 h of moderate-intensity endurance-type exercise.

Experimental physiology·2012
Same author

The anabolic response to resistance exercise and a protein-rich meal is not diminished by age.

The journal of nutrition, health & aging·2011
Same author

Social problems of the hospitalized elderly.

Canadian family physician Medecin de famille canadien·2010
Same author

The danger of weight loss in the elderly.

The journal of nutrition, health & aging·2008

Exercise impacts protein metabolism, increasing breakdown during activity and synthesis post-exercise, especially after resistance training. Amino acid availability appears key to muscle repair and growth.

Area of Science:

  • Exercise Physiology
  • Sports Nutrition
  • Muscle Metabolism

Background:

  • Exercise significantly affects protein metabolism, with varied whole-body responses reported.
  • Leucine oxidation increases during exercise, suggesting net protein breakdown.
  • Methodological limitations contribute to discrepancies in exercise and protein metabolism research.

Purpose of the Study:

  • To clarify the acute effects of different exercise types on whole-body and muscle protein metabolism.
  • To investigate the relationship between exercise, amino acid availability, and muscle protein synthesis.
  • To explore potential mechanisms driving post-exercise muscle protein adaptation.

Main Methods:

  • Analysis of existing literature on exercise and protein metabolism.

Related Experiment Videos

  • Distinguishing between whole-body and muscle-specific responses.
  • Reviewing studies on endurance and resistance exercise effects.

    • Main Results:

    • Exercise increases leucine oxidation and net protein breakdown.
    • Eccentric exercise elevates both protein breakdown and leucine oxidation.
    • Resistance exercise significantly increases muscle protein synthesis for up to 48 hours post-exercise.

    Conclusions:

    • Muscle protein synthesis and breakdown increase post-exercise, with synthesis potentially exceeding breakdown.
    • Increased amino acid availability, blood flow, and transport are linked to enhanced muscle protein synthesis.
    • Intracellular amino acid availability is proposed as a key regulator of post-exercise protein metabolism.