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[Experimental study of the biopreparation Lymphotilin as an antiproliferative and antitumor agent]
Iu V Tiagotin1, A E Polotskiĭ, T Ia Vakhitov
1State Research Institute of Super Pure Biopreparations, St. Petersburg.
Voprosy Onkologii
|May 14, 1998
Abstract:
We found in experiments involving the use of a biopreparation lymphotilin that its administration was followed by a decrease in proliferative activity of cultured tumor cells and a longer survival of mice bearing transplantable leukemia. An intensified intercalation of ethidium bromide in nucleic acids of tumor cells in lymphotilin culture points to the drug activity on nuclear level. Tumor cell inhibition by lymphotilin holds much promise for the practice of hematology.