Related Experiment Video
Updated: Aug 19, 2026

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
Published on: August 24, 2015
Reducing bacterial contamination of enteral feeds
C J Patchell1, A Anderton, C Holden
1Children's Hospital, Birmingham.
Insights
Implementing an improved enteral feeding protocol and staff training significantly reduced bacterial contamination in pediatric enteral feeds. Contamination rates dropped from 62% to 6% at home and 45% to 4% in hospitals.
Area of Science:
- Clinical Nutrition
- Infection Control
- Pediatric Healthcare
Background:
- Microbial contamination of enteral feeds is a common issue in pediatric patients.
- Previous studies indicate frequent bacterial contamination in both hospital and home enteral feeding settings.
Purpose of the Study:
- To evaluate the impact of an enhanced enteral feeding protocol and staff training on bacterial contamination.
- To determine the effectiveness of interventions in reducing microbial load in pediatric enteral nutrition.
Main Methods:
- Modified the enteral feeding protocol including alcohol disinfection, use of gloves, and extended feed reservoir use (24 hours).
- Collected and cultured daily feed samples from 16 pediatric inpatients and home-based patients.
- Compared contamination rates with historical control data.
Main Results:
- Significantly reduced enteral feed contamination rates from 62% to 6% for home-administered feeds (p < 0.001).
- Achieved a significant reduction in contamination rates from 45% to 4% for hospital-administered feeds (p < 0.001).
Conclusions:
- An optimized enteral feeding protocol is crucial for minimizing bacterial contamination.
- Regular and intensive staff training is essential for maintaining low contamination levels in enteral feeds.
- Interventions successfully reduced enteral feed contamination to acceptable levels.
Objective:
It has previously been shown that microbial contamination of enteral feeds given to children in hospital and at home is common. This study therefore examined the effects of improvements in the enteral feeding protocol, coupled with an intensive staff training programme, on bacterial contamination.
Methods:
The enteral feeding protocol was modified by: priming the feeding set on an alcohol treated metal tray, spraying the bottle opener and top with 70% alcohol, wearing non-sterile disposable gloves, and filling the feeding reservoir with feed for up to 24 hours' use rather than only four hours. Daily feeds samples were collected from 16 inpatients and home patients on enteral nutrition at the start and end of feeding. Seventy seven samples were cultured. Results were compared with previously published control data.
Results:
Enteral feed contamination rates were reduced significantly from 62% to 6% of feeds given at home (p < 0.001), and from 45% to 4% of feeds given in hospital (p < 0.001).
Conclusions:
This study highlights the importance of using an appropriate enteral feeding protocol, and of regular staff training in reducing contamination rates of enteral feeds to an acceptable level.
Related Concept Videos
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Methods for Controlling Microbial Growth
Physical Methods for Controlling Microbial Growth: Radiation and Filtration
Biological Methods for Microbial Control
Sources of Food Contamination

