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Related Experiment Videos

Age, experience and the changing brain

B Kolb1, M Forgie, R Gibb

  • 1Department of Psychology, University of Lethbridge, Alberta, Canada. Kolb@HG.ULETH.CA

Neuroscience and Biobehavioral Reviews
|May 14, 1998
PubMed
Summary
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Environmental factors significantly impact cortical structure across an animal's lifespan. This review examines how age, experience, sex, and brain injury interact to shape cortical plasticity.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Comparative Psychology

Background:

  • The adult brain exhibits plasticity, but the influence of early-life experiences on cortical development is complex.
  • Environmental enrichment and deprivation are known to alter brain structure and function.
  • Understanding age-dependent changes is crucial for addressing neurological disorders.

Purpose of the Study:

  • To review the effects of environmental experience on cortical structure across different ages.
  • To analyze the interplay between brain injury, sex, and age-dependent cortical plasticity.
  • To synthesize general conclusions regarding the influence of age, experience, sex, and injury on the cortex.

Main Methods:

  • Literature review and synthesis of existing research.

Related Experiment Videos

  • Analysis of studies investigating environmental enrichment/deprivation.
  • Examination of research on sex differences and brain injury effects on cortical development.

    • Main Results:

    • Environmental experiences significantly modify cortical structure in an age-dependent manner.
    • Brain injury and sex interact with age to influence the extent and nature of cortical plasticity.
    • Specific developmental windows show heightened sensitivity to environmental influences.

    Conclusions:

    • Cortical development is a dynamic process shaped by a complex interplay of age, experience, sex, and injury.
    • These factors have distinct and interactive effects on neuroplasticity throughout the lifespan.
    • Further research is needed to elucidate the precise mechanisms underlying these interactions for potential therapeutic interventions.