[Laryngeal sarcomatoid carcinoma: clinical, histological and immunohistochemical study of four cases]

The purpose of this study was to confirm how the use of immunohistochemical techniques can help to differentiate between tumors with a mixed proliferative pattern (epithelial and mesenchymal). It is fundamental to differentiating tumors of these characteristics in order to determine the prognosis and plan treatment. We used different techniques on tissue samples from four cases diagnosed as laryngeal sarcomatoid carcinoma. The results demonstrated that all four were sarcomatoid carcinomas, which correlated with the patients' favorable clinical evolution. The immunohistochemical study was useful for differentiating tumor type in the case of a biopsy specimen obtained from a mixed-pattern neoplasm.