Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endocardial electrograms and pacemaker sensing

P Hurzeler, V De Caprio, S Furman

    Medical Instrumentation
    |July 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Multidimensional gain control in image representation and processing in vision.

    Biological cybernetics·2014
    Same author

    Controlled synthesis of a large fraction of metallic single-walled carbon nanotube and semiconducting carbon nanowire networks.

    Nanoscale·2011
    Same author

    Cardiac Pacemaker Transtelephone Follow-up.

    IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society·2009
    Same author

    Cardiac pacemaker reliability.

    IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society·2009
    Same author

    Management of potential conflict of interest during publication and presentation.

    Journal of cardiac failure·2002
    Same author

    Recognition and correction of subcuticular malposition of pacemaker pulse generators.

    Pacing and clinical electrophysiology : PACE·2001

    Pacemaker sensing relies on electrogram voltage and slew rate. Chronic pacemaker use significantly reduces the average slew rate, impacting sensing capabilities over time.

    Area of Science:

    • Biomedical Engineering
    • Cardiology
    • Electrophysiology

    Background:

    • Implantable pacemakers rely on sensing endocardial electrograms to function.
    • Electrogram characteristics, including voltage and slew rate, are critical for pacemaker sensing circuits.
    • Changes in electrogram parameters from acute to chronic implantation can affect pacemaker performance.

    Purpose of the Study:

    • To compare acute and chronic endocardial electrogram parameters (peak-to-peak voltage and slew rate).
    • To investigate how these parameters change over time after pacemaker implantation.
    • To assess the implications of these changes for pacemaker sensing.

    Main Methods:

    • Recorded endocardial electrograms from 77 patients during acute pacemaker implantation.

    Related Experiment Videos

  • Recorded electrograms from 56 patients with chronic pacemaker lead usage (≥6 months).
  • Compared peak-to-peak voltage and slew rate between acute and chronic recordings.

    • Main Results:

    • The average slew rate in chronic cases was approximately half the average acute slew rate.
    • Maximum slew rate and voltage swing were observed during the intrinsic deflection of the electrogram.
    • Findings align with mathematical models of electrogram genesis and acute-to-chronic changes in stimulation thresholds.

    Conclusions:

    • Chronic pacemaker lead usage leads to a significant reduction in electrogram slew rate.
    • This reduction in slew rate may impact the reliability of pacemaker sensing over time.
    • Understanding these electrogram changes is crucial for optimizing pacemaker function and patient management.