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Related Experiment Videos

Correlation between bone mineral density and intervertebral disc degeneration

A Harada1, H Okuizumi, N Miyagi

  • 1Department of Orthopaedic Surgery, Chubu National Hospital, Obu, Japan.

Spine
|May 15, 1998
PubMed
Summary

Lower bone mass, particularly total body bone mineral density, is linked to increased intervertebral disc degeneration, including disc reduction and bulge. This finding is significant for understanding spinal diseases and osteoporosis in postmenopausal women.

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Area of Science:

  • Spine health
  • Osteoporosis research
  • Degenerative disc disease

Background:

  • Previous studies suggested an inverse correlation between osteoporosis and spondylosis.
  • However, these studies relied solely on radiographic findings, not directly assessing intervertebral disc changes.

Purpose of the Study:

  • To quantitatively investigate the relationship between bone mass and intervertebral disc degeneration.
  • To explore the correlation between bone mineral density and disc morphology.

Main Methods:

  • Measured intervertebral disc area and disc bulge ratio using MRI in 86 postmenopausal women.
  • Determined bone mineral density (total-body and lumbar) via dual-energy X-ray absorptiometry.
  • Analyzed the correlation between bone mass and disc degeneration parameters.

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Main Results:

  • Bone mineral density decreased significantly with age.
  • Disc area and disc bulge ratio did not correlate with age.
  • A negative correlation was found between bone mineral density and disc area, and a positive correlation between bone mineral density and disc bulge ratio.

Conclusions:

  • Bone mass, especially total body bone mineral density, is inversely correlated with intervertebral disc degeneration (reduction and bulge).
  • This inverse relationship is crucial for understanding degenerative spinal diseases and osteoporosis.