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Deficiency of the ninth component of complement in man
S Inai1, H Kitamura, S Hiramatsu
1Department of Immunology, Center for Adult Diseases, Osaka, Japan.
Journal of Clinical & Laboratory Immunology
|April 1, 1979
Abstract:
The studies of serum from a case with C9 (the ninth component of complement) deficiency are described. A 29-year-old woman in good health was found to have low serum complement levels (CH50). C9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. It was demonstrated that low CH50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (EA) by the complement components from C1 to C8.