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Alpha-fetoprotein serum concentration in different stages of liver cirrhosis
A Wiercińska-Drapało1, R Flisiak, D Prokopowicz
1Department of Infectious Diseases, Medical Academy of Białystok.
Roczniki Akademii Medycznej W Bialymstoku (1995)
|January 1, 1997
Abstract:
Serum alpha-fetoprotein (AFP) concentration was measured in 41 patients with different stages of liver cirrhosis demonstrated through scored Child-Pugh classification. Mean value was elevated up to 65.9 21.9 U/l, butstatistically significant difference in comparison with control group was observed only in patients classified as Child-Pugh C. AFP concentration revealed significant positive correlation with score values. Dynamics of AFP during one-year follow up demonstrated three-fold and statistically significant increase of its concentration, that was accompanied by elevation of mean score values.