Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Caroli's disease: 1977-1995 experiences

U Dağli1, F Atalay, N Saşmaz

  • 1Department of Gastroenterology, Yüksek Ihtisas Hospital, Ankara, Turkey.

European Journal of Gastroenterology & Hepatology
|May 15, 1998
PubMed
Summary

Caroli's disease, a rare congenital cystic dilatation of intrahepatic bile ducts, is increasingly diagnosed. Treatment focuses on improving biliary drainage and symptom relief for patients with this condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incremental value of binary PSMA PET nodal status when added to Briganti-2019 and MSKCC models for predicting pathologic lymph node metastasis in prostate cancer.

Actas urologicas espanolas·2026
Same author

The effect of acute cold ischemia duration on testicular tissue.

BMC urology·2026
Same author

Awareness and obscurity: demystifying genomic profiling in real-world practice for the members of the Turkish Society of Medical Oncology (TSMO).

European review for medical and pharmacological sciences·2023
Same author

Nasal secretory protein changes following intravenous choline administration in calves with experimentally induced endotoxaemia.

Veterinary immunology and immunopathology·2021
Same author

Results of Liquid Biopsy Studies by Next Generation Sequencing in Patients with Advanced Stage Non-small Cell Lung Cancer: Single Center Experience from Turkey.

Balkan journal of medical genetics : BJMG·2020
Same author

Drainless resection of the submandibular gland with facial vessel preservation: A comparative study.

Journal of stomatology, oral and maxillofacial surgery·2020

Area of Science:

  • Hepatology
  • Gastroenterology
  • Surgical Gastroenterology

Background:

  • Caroli's disease, characterized by congenital cystic dilatation of intrahepatic bile ducts, was historically underdiagnosed.
  • Recent advancements in diagnostic imaging have led to increased recognition of this rare condition.

Purpose of the Study:

  • To analyze and discuss clinical observations and treatment outcomes in 21 adult patients diagnosed with Caroli's disease.
  • To highlight the diagnostic trends and therapeutic strategies for Caroli's disease.

Main Methods:

  • A retrospective analysis of 21 adult patients diagnosed with Caroli's disease between 1977 and 1995.
  • Evaluation of presenting symptoms, disease distribution, coexisting hepatobiliary conditions, and treatment modalities including surgery and endoscopic procedures.

Related Experiment Videos

Main Results:

  • Abdominal pain was the most frequent symptom (18/21 patients).
  • Biliary lesions were bilobar in 12 patients and monolobar in nine; two had congenital hepatic fibrosis.
  • Coexisting hepatobiliary disease was present in all patients, with 95% experiencing cystolithiasis or cholelithiasis. Surgical intervention was performed in 18 patients, with varied outcomes and four deaths during follow-up.

Conclusions:

  • Caroli's disease is diagnosed more frequently due to improved diagnostic capabilities.
  • Effective treatment aims to achieve adequate biliary drainage and alleviate patient symptoms.