Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

JADE: an approach for interconnecting bioinformatics databases

L D Stein1, S Cartinhour, D Thierry-Mieg

  • 1MIT, WI/MIT Center for Genome, Cambridge, MA, USA.

Gene
|May 16, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HopX1 in Erwinia amylovora functions as an avirulence protein in apple and is regulated by HrpL.

Journal of bacteriology·2011
Same author

Complete genome sequence of the plant pathogen Erwinia amylovora strain ATCC 49946.

Journal of bacteriology·2010
Same author

Genetic analyses on DNA microarrays.

Current protocols in human genetics·2008
Same author

Navigating public physical mapping databases.

Current protocols in human genetics·2008
Same author

A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome.

EMBO reports·2001
Same author

Computational and experimental analysis of microsatellites in rice (Oryza sativa L.): frequency, length variation, transposon associations, and genetic marker potential.

Genome research·2001
Same journal

TBX6 promotes proliferation, invasion, and migration in colorectal cancer: Integrated transcriptomic and protein interaction network analysis.

Gene·2026
Same journal

Face/off: phase-specific modeling of lineage plasticity using near-patient models in genitourinary cancers.

Gene·2026
Same journal

Hierarchical analysis of metabolic phenotype reveals distinct microbiota and circulatory transcriptome in metabolic dysfunction-associated steatotic liver disease.

Gene·2026
Same journal

Mutation T71R enhanced the structural stability and functional activity of wild type superoxide dismutase cloned from soil metagenome.

Gene·2026
Same journal

Reduced ATXN1 expression as an adverse prognostic indicator in Acute myeloid leukemia.

Gene·2026
Same journal

Constructing regulatory networks of Rubisco post-translational modifications: a novel avenue for engineering environment adaptive plants.

Gene·2026
See all related articles

A new software, Jade, integrates diverse biological data from sources like Genbank. This enables the creation and reuse of bioinformatics tools without altering original data, promoting data accessibility and analysis.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Integration

Background:

  • Biological data is increasingly available online from diverse sources (e.g., GDB, Genbank, Acedb).
  • Integrating and analyzing this distributed data presents significant challenges for researchers.
  • Existing methods often require modifications to the original data sources, limiting interoperability.

Purpose of the Study:

  • To develop a software solution for seamless integration of heterogeneous biological data.
  • To enable the creation of reusable and interchangeable analytical tools and interfaces for bioinformatics data.
  • To facilitate data analysis without necessitating changes to the underlying data repositories.

Main Methods:

  • Development of the Jade software system.

Related Experiment Videos

  • Implementation using the Java programming language for cross-platform compatibility (Macintosh, Windows, Unix).
  • Design focused on enabling tool interchangeability and reuse.
  • Main Results:

    • Jade successfully integrates biological data from multiple web-based sources.
    • Programmers can develop custom analytic tools and graphical user interfaces.
    • Tools created with Jade can be reused across different data sources without modification.

    Conclusions:

    • Jade provides a flexible and efficient platform for biological data integration.
    • The software enhances the accessibility and analytical potential of distributed bioinformatics resources.
    • Jade is freely available, promoting widespread adoption and collaboration in biological data analysis.