[Permeability of blood-aqueous humor barrier in primary open-angle glaucoma]

Biochemical changes in the chamber humor play an important role in the pathogenesis of primary open-angle glaucoma and are largely determined by the permeability of the blood-eye barrier. Comparative study of total protein content in the chamber humor in mature and far advanced glaucoma showed that the disease involves a progressive increase in the permeability of the blood-aqueous humor barrier, which may be due to dystrophic changes in ocular tissues in the course of glaucoma progress and accumulation of metabolites damaging the biological membranes in the chamber fluid or to antiglaucoma drugs increasing the permeability of the blood-humor barrier.