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[Beta trace protein in the cerebrospinal fluid and serum in meningoencephalitis]
A J Dorta-Contreras1, H Reiber, E Agüero-Valdés
1Laboratorio de Neuroinmunología, Hospital Pediátrico San Miguel del Padrón, La Habana, Cuba.
Introduction:
beta-trace protein or D2 prostaglandin synthase is a dual functional protein. Its role and clinical value in cerebrospinal fluid is under study.
Material And Methods:
Seventy four pediatric patients suffering from viral meningoencephalitis and 7 with bacterial meningoencephalitis were studied. Sera and cerebrospinal fluid samples were taken. Albumin and beta-trace protein were quantified by immunodiffusion and nephelometry respectively.
Results:
Increased cerebrospinal fluid beta-trace protein levels in comparison with normal value were observed. Nevertheless such expected increment was no possible seen in bacterial meningoencephalitis.
Conclusions:
beta-trace protein may contribute with the etiological diagnosis in meningoencephalitis.