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[Prostatic xanthoma]

E Redondo Martínez1, A Rey López

  • 1Servicio de Anatomía Patológica, Hospital Ntra. Sra. del Pino, Las Palmas de Gran Canaria, España.

Archivos Espanoles De Urologia
|May 20, 1998
PubMed
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Prostatic xanthoma is a rare, benign inflammatory condition. Histological examination reveals foamy macrophages, aiding diagnosis in cases presenting as a palpable mass.

Area of Science:

  • Urology
  • Pathology

Background:

  • Prostatic xanthoma is a rare, benign inflammatory condition.
  • It is often associated with granulomatous prostatitis.

Observation:

  • A 70-year-old male presented with voiding symptoms and a prostate exam suggestive of hyperplasia.
  • Initial prostate biopsy was negative; transurethral resection revealed benign prostatic hyperplasia with sclerosing adenosis.
  • Histology showed clear, foamy cells identified as macrophages (CD-68 positive), with negative cytokeratin staining.

Findings:

  • The case highlights the histological features of prostatic xanthoma, characterized by foamy macrophages.
  • Immunocytochemistry confirmed the presence of macrophages and ruled out epithelial proliferation.

Implications:

Related Experiment Videos

  • Prostatic xanthoma, though rare, can mimic other prostatic conditions and present as a palpable mass.
  • Accurate histological diagnosis is crucial, but the condition is generally benign and clinically insignificant.