Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Pregnancy after bone marrow transplantation

S C Gulati¹, C Van Poznak

¹New York Hospital Cornell Medical Center, New York, USA. gulati1@aol.com

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|May 20, 1998

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neratinib and ado-trastuzumab emtansine for pretreated and untreated human epidermal growth factor receptor 2 (HER2)-positive breast cancer brain metastases: Translational Breast Cancer Research Consortium trial 022.

Annals of oncology : official journal of the European Society for Medical Oncology·2024

Same author

Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations.

Journal of bone oncology·2021

Same author

Bone health in cancer: ESMO Clinical Practice Guidelines.

Annals of oncology : official journal of the European Society for Medical Oncology·2020

Same author

Anti-vascular endothelial growth factor antibody monotherapy causes destructive advanced periodontitis in rice rats (Oryzomys palustris).

Bone·2019

Same author

Zoledronic acid increases the prevalence of medication-related osteonecrosis of the jaw in a dose dependent manner in rice rats (Oryzomys palustris) with localized periodontitis.

Bone·2018

Same author

Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases.

Annals of oncology : official journal of the European Society for Medical Oncology·2011

Pregnancy after bone marrow transplantation (BMT) is possible, with over 250 reported births. Fertility concerns for BMT survivors require careful counseling regarding potential complications.

Area of Science:

Reproductive Medicine
Hematology
Oncology

Background:

Bone marrow transplantation (BMT) involves high-dose chemotherapy and radiation.
These treatments can lead to gonadal dysfunction and impact fertility.
BMT patients are often young and desire a normal quality of life, including parenthood.

Purpose of the Study:

To evaluate the occurrence of pregnancy following bone marrow transplantation.
To assess the feasibility of conception and childbirth in BMT survivors.

Main Methods:

A comprehensive literature review of reported pregnancies in the BMT population.
Analysis of case reports and series studies published in English.

Main Results:

Related Experiment Videos

Over 250 offspring have been reported from BMT recipients.
Multiple case reports and series studies confirm successful pregnancies post-BMT.

Conclusions:

Pregnancy is achievable for many bone marrow transplant survivors.
Counseling BMT patients on fertility, pregnancy risks, and birth defects is crucial and complex.
Further investigation is needed to address the evolving complexities of fertility and pregnancy in BMT survivors.