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Related Experiment Videos

Copper absorption and bioavailability

R A Wapnir1

  • 1Department of Pediatrics, North Shore University Hospital, New York University School of Medicine, Manhasset 11030, USA. rwapnir@nshs.edu

The American Journal of Clinical Nutrition
|May 20, 1998
PubMed
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The human body absorbs 30-40% of dietary copper via a specific transport system. Factors like aging, diet composition, and gastrointestinal health significantly influence copper absorption and homeostasis.

Area of Science:

  • Nutritional Science
  • Gastroenterology
  • Human Physiology

Background:

  • The human gastrointestinal system absorbs 30-40% of dietary copper.
  • Copper absorption involves a carrier-mediated transport mechanism with micromolar affinity.
  • Copper homeostasis may be affected by aging, sex, and diet.

Purpose of the Study:

  • To review factors influencing copper absorption and bioavailability.
  • To explore the implications of copper homeostasis for health and disease.
  • To identify dietary and pharmacologic strategies for modulating copper status.

Main Methods:

  • Literature review of experimental data on copper absorption.
  • Analysis of physiological factors affecting copper homeostasis.

Related Experiment Videos

  • Evaluation of dietary components and their impact on copper bioavailability.

    • Main Results:

    • Copper absorption efficiency is influenced by diet, aging, and sex.
    • Mineral supplements, dietary fiber, proteins, and organic acids can modulate copper absorption.
    • Gastrointestinal diseases can impair copper uptake.

    Conclusions:

    • Copper absorption is a complex process influenced by multiple factors.
    • Dietary modifications and specific interventions show potential for managing copper status.
    • Understanding copper bioavailability is crucial for preventing and treating copper-related disorders like Wilson disease.