Serum cholesterol and haematology at age eight to ten years

The aim of the study was to estimate 95% reference ranges for blood constituents in 9-year-old children. Venepuncture was successful in 753 white children age 8-9 years in 21 areas in England and 5 in Scotland. Agreement with published reference ranges for haematological measurements from undocumented samples was good. The reference ranges were 3.22 to 5.79 mmol/l for serum total cholesterol, 0.9 to 2.1 mmol/l for high density lipoprotein cholesterol, and 13 to 61 micrograms/l for ferritin. The upper limit for total cholesterol is well above the recommended level for adults, with 9.3% of children having a value of 5.2 mmol/l or more. The results provide a scientific basis for ranges previously published for haematological measurements. Documented data should be combined from national studies to provide further reference ranges for routine use.