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Updated: Aug 12, 2026

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
[New biological factors of thromboses]
Z Tazi-Mezalek1, T Mekouar, P Cacoub
1Service de Médecine Interne A, Hôpital IBN-SINA, Rabat, Maroc.
Abstract:
Hypercoagulability states are caused by a disturbance of blood rheology due to the presence or pathological absence of a clotting factor. These abnormalities of haemostasis are essentially studied in the context of venous thrombosis. Over the years, in parallel with the progress in therapeutics, new laboratory abnormalities have been discovered and other, previously described, factors have been recently correlated with thrombotic phenomena. Based on a review of the literature, the authors describe the pathogenic role and the place of these various laboratory abnormalities in thromboembolic disease.
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