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Unilateral Meesmann's dystrophy

A Goldberg1, U Schlötzer-Schrehardt, T Seiler

  • 1Department of Ophthalmology, University of Dresden, Germany.

International Ophthalmology
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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This study details the first reported case of unilateral Meesmann's epithelial dystrophy. Autologous stem cell transplantation from the healthy eye successfully treated frequent corneal erosions.

Area of Science:

  • Ophthalmology
  • Corneal Diseases
  • Histopathology

Background:

  • Meesmann's epithelial dystrophy is a rare, bilateral, autosomal dominant corneal condition.
  • Typically presents with bilateral corneal microcysts and epithelial abnormalities.

Observation:

  • A unique case of unilateral microcystic Meesmann's epithelial dystrophy was observed in the left cornea of a 43-year-old patient.
  • Histological examination revealed a distinctive 'peculiar substance' within epithelial cysts and corneal epithelial cells, confirming the unilateral diagnosis.

Findings:

  • The patient experienced frequent corneal erosions due to the unilateral condition.
  • Autologous stem cell transplantation was performed using cells from the unaffected right eye to address the erosions.

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Implications:

  • This case expands the known clinical spectrum of Meesmann's epithelial dystrophy.
  • Successful autologous stem cell transplantation offers a potential therapeutic strategy for unilateral presentations and associated complications like corneal erosions.