Opportunities in drug discovery for treatment of AIDS

5,6-Diaminocytidine, a versatile synthon for pyrimidine-based bicyclic nucleosides.

Organic letters·2000

PMTI, a broadly active unusual single-stranded polyribonucleotide, inhibits human immunodeficiency virus replication by multiple mechanisms.

Antiviral chemistry & chemotherapy·1999

Antiviral oligo- and polyribonucleotides containing selected triazolo[2,3-a]purines.

Journal of medicinal chemistry·1998

Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii.

Journal of medicinal chemistry·1996

Probing nucleic acid geometries: oligonucleotides containing 2'-O-phenethyladenosine at specific sites.

Bioconjugate chemistry·1996

Self-complementary oligodeoxyribonucleotides containing 2'-O-(anthraquinone-2-methyl)adenosine.

Bioconjugate chemistry·1995

Development of Sustained Release Chitosan/β-Glycerol Phosphate-Based Injectable Thermo-Gels Containing Naproxen Sodium: In-Vitro and In-Vivo Evaluation.

Pharmaceutical research·2026

Liposomal Formulation of a Tetravalent Oxaliplatin Prodrug: Preparation and Antitumor Efficacy.

Pharmaceutical research·2026

Mechanistic Insights into Poloxamer 188-Mediated Stabilization of AAV8 Capsids Using Coarse-Grained Molecular Dynamics.

Pharmaceutical research·2026

Biosurfactant-Based Interventions for Improving Lung Function and Controlling Inflammation.

Pharmaceutical research·2026

Controlled Release of the IL-1R Antagonist, Anakinra, from Microgels with an Extended Intra-articular Residence Time.

Pharmaceutical research·2026

Federated Estimation of Population Pharmacokinetic Models with Exact Equivalence to Pooled-Data Analysis.

Pharmaceutical research·2026

De Novo Discovery of Bioactive Cyclic Peptides via Cellular Selection of Genetically Encoded Libraries.

Chembiochem : a European journal of chemical biology·2026

Antioxidant Potential of Schistocerca gregaria (Orthoptera: Acrididae) Extract: HPLC Analysis, Molecular Docking, and Bioassays.

Chemistry & biodiversity·2026

Machine learning of honey bee olfactory behavior identifies repellent odorants in free-flying bees in the field.

eLife·2026

Synthetic strategies toward structurally diverse seven-membered ε-sultams: a review.

Chemical communications (Cambridge, England)·2026

Comparative Study of the Antioxidant Mediated Antiaging Properties of Endocarp Extracts From Phoenix dactylifera and Phoenix dactylifera L. via In Silico and In Vitro Analysis.

Food science & nutrition·2026

Efficacy and Safety of Cannabinoid-Based Interventions for Low Back Pain and Migraine: A Systematic Review of Randomized Controlled Trials.

Cannabis and cannabinoid research·2026

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5,6-Diaminocytidine, a versatile synthon for pyrimidine-based bicyclic nucleosides.

PMTI, a broadly active unusual single-stranded polyribonucleotide, inhibits human immunodeficiency virus replication by multiple mechanisms.

Antiviral oligo- and polyribonucleotides containing selected triazolo[2,3-a]purines.

Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii.

Probing nucleic acid geometries: oligonucleotides containing 2'-O-phenethyladenosine at specific sites.

Self-complementary oligodeoxyribonucleotides containing 2'-O-(anthraquinone-2-methyl)adenosine.

Development of Sustained Release Chitosan/β-Glycerol Phosphate-Based Injectable Thermo-Gels Containing Naproxen Sodium: In-Vitro and In-Vivo Evaluation.

Liposomal Formulation of a Tetravalent Oxaliplatin Prodrug: Preparation and Antitumor Efficacy.

Mechanistic Insights into Poloxamer 188-Mediated Stabilization of AAV8 Capsids Using Coarse-Grained Molecular Dynamics.

Biosurfactant-Based Interventions for Improving Lung Function and Controlling Inflammation.

Controlled Release of the IL-1R Antagonist, Anakinra, from Microgels with an Extended Intra-articular Residence Time.

Federated Estimation of Population Pharmacokinetic Models with Exact Equivalence to Pooled-Data Analysis.

De Novo Discovery of Bioactive Cyclic Peptides via Cellular Selection of Genetically Encoded Libraries.

Antioxidant Potential of Schistocerca gregaria (Orthoptera: Acrididae) Extract: HPLC Analysis, Molecular Docking, and Bioassays.

Machine learning of honey bee olfactory behavior identifies repellent odorants in free-flying bees in the field.

Synthetic strategies toward structurally diverse seven-membered ε-sultams: a review.

Comparative Study of the Antioxidant Mediated Antiaging Properties of Endocarp Extracts From Phoenix dactylifera and Phoenix dactylifera L. via In Silico and In Vitro Analysis.

Efficacy and Safety of Cannabinoid-Based Interventions for Low Back Pain and Migraine: A Systematic Review of Randomized Controlled Trials.

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Opportunities in drug discovery for treatment of AIDS

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