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Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

Published on: February 21, 2015

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies

S Knuutila1, A M Björkqvist, K Autio

  • 1Laboratory of Medical Genetics, Helsinki University Central Hospital, Finland. sakari.knuutila@helsinki.fi

The American Journal of Pathology
|May 20, 1998
PubMed

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Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...