Central serous chorioretinopathy in two families
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Updated: Oct 29, 2026

Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis
Published on: September 7, 2021
D W Park1, H Schatz, M M Gaffney
1Department of Ophthalmology, California Pacific Medical Center, San Francisco, USA.
Purpose And Methods:
The reported occurrence of central serous chorioretinopathy (CSCR) in families is rare. We report two families (five patients) who have been diagnosed with CSCR. The diagnosis of CSCR was made on clinical and fluorescein angiographic findings.
Results:
Three members of the first family and two members of the second family had CSCR. Affected individuals were all males.
Conclusions:
CSCR has been associated with psychological and emotional stress and the occurrence of CSCR in families may be due to similar inherited psychological and physiological characteristics and responses that predispose these families to the development of CSCR.
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