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[Pathological examination of 10 eyes with silicone oil injection]
1Department of Ophthalmology, Third Hospital, Beijing Medical University.
Objective:
To find the histopathologic findings about 10 eyes of 10 patients with silicone oil injection.
Methods:
The operative procedures included retinal detachment surgery, pars plana vitrectomy and silicone oil injection. The globes were enucleated 4 to 27 months after silicone oil injection. Paraffin sections were made for light microscopic examination.
Results:
The retina showed severe degeneration, pre- and sub-retinal membranous fibrous tissue proliferation. The round empty vacuoles formed by silicone oil could be seen in the proliferative membrane.
Conclusions:
It is demonstrated that silicone oil has great toxic effect to the detached retina and it may stimulate the development of proliferative vitreoretinopathy.