Related Experiment Videos
Light and electron microscopic observations on rat molar periodontal ligament after intraperitoneal injection of
A H Salama1, N A Lashin, M A Ali
1Faculty of Oral and Dental Medicine, Cairo University.
Egyptian Dental Journal
|July 1, 1993
Abstract:
The effect of intraperitoneal injection of Vinblastine sulfate on rat periodontal ligament was studied. Cells still synthetize collagen after 2 hours of the injection with evidence of loss of extracellular collagen fibers orientation. Tubular lysosome could not be detected after 2 hours with formation of lysosomal clusters in the cell center. After 4 hours of administration, evidences of cell degeneration were observed. The present study has shown that Vinblastine produces effect on fibroblasts as early as two hours after injection.