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Synovial sarcoma: oncological and functional results

H J van der Heide1, R P Veth, M Pruszczynski

  • 1Department of Orthopaedics, University Hospital, Nijmegen, The Netherlands.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|May 20, 1998
PubMed
Summary

Synovial sarcoma treatment outcomes were poor, with a high rate of pulmonary metastases and mortality. Functional results varied, with some patients experiencing complications like scarring and venous insufficiency.

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Area of Science:

  • Orthopedic Oncology
  • Surgical Oncology
  • Sarcoma Research

Background:

  • Synovial sarcoma is a rare soft tissue sarcoma.
  • Treatment efficacy and long-term outcomes require further investigation.

Purpose of the Study:

  • To evaluate oncological and functional outcomes of synovial sarcoma treatment.
  • Retrospective review of 20 patients treated at Nijmegen University Hospital.

Main Methods:

  • Retrospective review of 20 synovial sarcoma patients.
  • Analysis of tumor location, surgical stage (Enneking), and surgical margins.
  • Assessment of oncological outcomes (metastasis, recurrence, survival) and functional results (MSTS score).

Main Results:

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  • Most common tumor location: lower extremity (12/20).
  • High incidence of metastatic disease, with 8/12 patients developing metastases during follow-up.
  • 14/20 patients died of metastatic disease; 4/20 had no evidence of disease at follow-up.

    • Conclusions:

    • Synovial sarcoma treatment outcomes are generally poor, primarily due to pulmonary metastases.
    • Functional outcomes varied, with some patients experiencing complications impacting their MSTS scores.