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Women of reproductive age with endometriosis are not osteopenic
U Ulrich1, R Murano, M A Skinner
1University of Washington, Seattle, USA.
Objective:
To determine whether women of reproductive age with endometriosis are osteopenic and whether bone density decreases with higher stages of endometriosis.
Design:
A multicenter cross-sectional study was performed.
Setting:
Thirty-nine gynecological clinics in the United States, Canada, and Puerto Rico.
Patient(S):
Two hundred forty-one women of reproductive age with laparoscopically proved endometriosis.
Intervention(S):
Diagnostic laparoscopy, bone densitometry.
Main Outcome Measure(S):
Endometriosis stages according to the criteria of the American Society for Reproductive Medicine, lumbar spine bone mineral density (L2-L4) as measured by dual-energy x-ray absorptiometry.
Result(S):
The mean lumbar spine bone mineral density, as well as the distribution of bone mineral density, of the women with endometriosis was similar to that of a normal population. There were no significant differences between endometriosis stage groups I-IV regarding bone mineral density as well as body weight, body mass index, and height.
Conclusion(S):
Women of reproductive age with endometriosis are not osteopenic. More advanced stages of endometriosis are not associated with a decrease in lumbar spine bone mineral density.