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Concomitant lichen scrofulosorum and erythema induratum
1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul.
Journal of the American Academy of Dermatology
|May 20, 1998
Summary
Simultaneous tuberculids, lichen scrofulosorum and erythema induratum occurred in a patient. Despite negative PCR, lesions resolved with antituberculous chemotherapy, suggesting a link.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Tuberculids are inflammatory skin reactions to tuberculosis.
- Lichen scrofulosorum and erythema induratum are distinct forms of tuberculids.
Observation:
- A patient presented with concurrent lichen scrofulosorum and erythema induratum.
- Clinical and histopathologic findings were characteristic of tuberculids.
- A positive Mantoux test indicated tuberculosis exposure.
Findings:
- No evidence of active extracutaneous tuberculosis was found.
- Mycobacterial DNA was not detected in skin lesions via PCR.
- Rapid improvement of skin lesions was observed with antituberculous chemotherapy.
Implications:
- This case highlights the simultaneous occurrence of two tuberculid types.
- It suggests a potential diagnostic and therapeutic role for chemotherapy in managing tuberculids, even with negative PCR.
- Further research may clarify the pathogenesis and diagnostic criteria for co-occurring tuberculids.