Related Experiment Video
Updated: Aug 9, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Clinical and histologic trends of melanoma
T M Johnson1, O M Dolan, T A Hamilton
1Department of Dermatology, University of Michigan Medical Center, Ann Arbor, USA.
Background:
Several changing clinical and histopathologic melanoma trends occurred from the 1950s to the 1980s.
Objective:
The purpose of this study was to evaluate melanoma trends during the past decade and to compare present trends to those documented during the past four decades.
Methods:
Sex, age at diagnosis, location, tumor thickness, stage, and histologic subtypes were evaluated from 1984 to 1995 and compared with trends during the past four decades.
Results:
Most changing trends from the past four decades have slowed or stabilized during the past decade.
Conclusion:
Complete reporting of all melanomas to central tumor registries is necessary to accurately analyze present and future melanoma trends. Ongoing and new prevention and control strategies beginning at birth may be necessary to continue the positive efforts to curtail the melanoma epidemic.
Related Concept Videos
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

