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Excimer laser for various degrees of myopia. A new model estimating the immediate response, the regression, the final
1Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark.
Purpose:
To demonstrate a unified model for various degrees of myopia, characterizing the response-time relationship and its influence of topical corticosteroids.
Methods:
84 eyes were treated with excimer laser for myopia (median -7.1 D). 50 eyes received topical NSAID for 4 days (group 1), and 34 eyes (group 2) were further treated postoperatively with bandage lens and topical corticosteroids for three months. The response-time relationship was expressed as P(t)=a+b*exp(k*t), where P(t) is the response expressed as the percent change in dioptric power to the postoperative time t, a is the final percent response, b is the total percent regression and k the time constant. a+b express the percent immediate response and T1/2=0.69/k denote the time within which half of the total regression has occurred.
Results:
The immediate and final responses were significantly larger in group 2 (128.9% and 70.5%) compared with group 1 (110.5% and 59.8%). T1/2 was significantly longer in group 2 (2.1 month) compared with group 1 (0.8 month)
Conclusion:
Use of bandage lens together with steroids significantly influences the response-time relationship after excimer laser treatment for myopia.