Atypical microangiopathy in a patient treated with ticlopidine

Microangiopathies are rare complications during treatments with ticlopidine. We describe an atypical microangiopathy, affecting almost exclusively myocardium, and thrombocytopenia, shortly after onset of ticlopidine. The patient died a few days after. Autopsy showed no bleedings or large thrombi in most organs, but were compatible with microangiopathy in myocardial small vessels.