Related Experiment Video

Updated: Aug 4, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Risk factors for hemiretinal vein occlusion: comparison with risk factors for central and branch retinal vein

R D Sperduto1, R Hiller, E Chew

  • 1National Eye Institute, Bethesda, Maryland 20892-2510, USA.

Ophthalmology
|May 21, 1998
PubMed

Insights

Systemic hypertension, diabetes, and glaucoma are key risk factors for various retinal vein occlusions. Lifestyle factors like physical activity and alcohol consumption may reduce central retinal vein occlusion risk.

Area of Science:

  • Ophthalmology
  • Vascular Medicine
  • Epidemiology

Background:

  • Retinal vein occlusions (RVOs) are a significant cause of vision loss.
  • Understanding distinct risk factor profiles for hemiretinal (HRVO), central (CRVO), and branch (BRVO) retinal vein occlusions is crucial for targeted prevention and management.

Purpose of the Study:

  • To identify and compare potential risk factors for hemiretinal vein occlusion (HRVO) with those of central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO).

Main Methods:

  • A multicenter case-control study involving 79 HRVO, 258 CRVO, 270 BRVO patients, and 1142 controls.
  • Risk factor data collected via interviews, clinical exams, and laboratory blood analyses.

Main Results:

  • Systemic hypertension and diabetes mellitus increased HRVO risk.
  • CRVO risk was linked to diabetes, hypertension, and erythrocyte sedimentation rate (females), while reduced by physical activity and alcohol.
  • BRVO risk correlated with hypertension, BMI, and alpha2-globulin, but decreased with HDL and alcohol.
  • Glaucoma history was a risk factor for all three RVO types.

Conclusions:

  • Patients with retinal vein occlusions require evaluation for cardiovascular disease, diabetes, and glaucoma.
  • These findings aid in stratifying risk and developing preventative strategies for different RVO subtypes.
Abstract

More Related Videos

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...