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Proliferative vitreoretinopathy: a natural history of the fellow eye
1Jules Stein Eye Institute, Retina Division, Los Angeles, California, USA.
Objective:
To determine how often the fellow eyes of patients with proliferative vitreoretinopathy (PVR) harbor a vision-threatening condition at presentation; to determine how often the fellow eyes of patients with PVR develop vision-threatening conditions; and to determine how often the fellow eyes of patients with PVR lose vision.
Design:
A retrospective case review design was used.
Participants:
Two hundred and forty-nine patients with PVR were studied.
Intervention:
The authors observed the fellow eye of eyes with PVR for vision-threatening pathology.
Main Outcome Measures:
The primary anatomic endpoint of this study was the detection of vision-threatening pathology in the fellow eye of patients with PVR. Secondary outcome measures included the development of visual loss in the fellow eye.
Results:
A wide variety of vision-threatening conditions were diagnosed in the fellow eyes of patients with PVR. Of patients meeting entry criteria with reliable follow-up data, greater than 50% of fellow eyes demonstrated vision-threatening pathology at some point during follow-up.
Conclusions:
Patients who develop PVR in one eye are at considerable risk for developing vision-threatening pathology or vision-damaging conditions in the fellow eye. This information should be carefully considered when making surgical decisions in patients facing PVR surgery.