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Related Experiment Videos

The hypnic ("alarm clock") headache syndrome

D W Dodick1, A C Mosek, J K Campbell

  • 1Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA.

Cephalalgia : an International Journal of Headache
|May 22, 1998
PubMed
Summary

Hypnic headache syndrome, a rare sleep disorder, often awakens patients at night. While some treatments show promise, managing this condition remains challenging.

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Area of Science:

  • Neurology
  • Sleep Medicine

Background:

  • Hypnic headache syndrome is a rare, benign, sleep-related headache disorder.
  • Characterized by nocturnal headaches, it significantly impacts sleep quality.

Purpose of the Study:

  • To describe the clinical features and outcomes of hypnic headache syndrome.
  • To evaluate treatment efficacy and patient responses.

Main Methods:

  • Retrospective case series of 19 patients with hypnic headache syndrome.
  • Follow-up data collection on headache characteristics, treatment responses, and outcomes.

Main Results:

  • Headaches typically occurred during sleep, often at consistent times (1-3 a.m.).
  • High frequency of headaches (more than 4 nights/week) was reported by 68% of patients.
  • Medication provided permanent suppression in 24% of patients; caffeine was helpful for some.

Conclusions:

  • Hypnic headache syndrome presents with consistent nocturnal awakenings.
  • Effective long-term management remains a challenge, with limited treatment options.
  • Further research is needed to explore novel therapeutic strategies.

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