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[Detection of Chlamydia trachomatis and Ureaplasma urealyticum from aborted tissues by polymerase chain reaction
Objective:
To study the prevalence of Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) infection in spontaneous abortion patients.
Methods:
CT and UU in aborted tissues were determined by polymerase chain reaction (PCR) technique in 45 spontaneous abortion patients (abortion group) and 25 artificial abortion cases (control group).
Results:
The detective rate of CT and UU was 42.2% and 33.3% respectively in the abortion group. As compared with the control group significant difference (P < 0.01, P < 0.025) was shown. The detection rate of mixed CT and UU is 8.9%.
Conclusion:
CT and UU are important infection factors which may cause spontaneous abortion. PCR examination of the aborted tissue can submit an accurate, rapid microorganic diagnosis of CT and (or) UU infection.