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Deep penetrating dermatofibroma
1Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock 72205, USA.
Background:
Deep penetrating dermatofibroma is an unusual and histologically distinctive form of dermatofibroma that usually occurs on the lower extremities of adults.
Objective:
The dermatologic surgeon and pathologist should be aware of this entity to prevent excessive treatment of a benign condition.
Methods:
We are reporting a case of deep penetrating dermatofibroma with the results of histologic examination and immunohistochemical studies.
Results:
The neoplasm consisted of a fibrohistiocytic tumor penetrating into the subcutis accompanied by scalloped extensions along the septae. Immunohistochemical stains were positive for Factor XIIIa and negative for CD34.
Conclusion:
Recognition of the histologic pattern is important in distinguishing deep penetrating dermatofibroma from dermatofibrosarcoma protuberans.